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Onsior (Robenacoxib) Dose for Cats & Dogs: Strengths & Dose Calculator

Onsior is robenacoxib from Elanco: 6 mg tablets for cats at 1 mg/kg once a day [1], and a 20 mg/mL injection for cats and dogs at 2 mg/kg under the skin once a day [2] — both for post-operative pain, for a maximum of 3 days [1][2].

Contains
Robenacoxib
Company
Elanco
Forms
Onsior 6 mg tablet for cats
Onsior injection 20 mg/mL
Label species
Cats, Dogs
Data from
USA (FDA label)
Type
NSAID / pain relief

Onsior dose calculator

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Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.

Onsior strengths and presentations

PresentationContainsStrength check
Onsior 6 mg tablet for cats
PO
Robenacoxib 6 mg per tablet[1]Confirmed
Onsior injection 20 mg/mL
SC
Robenacoxib 20 mg per mL[2]Confirmed
Onsior 6 mg tablet for cats — by body weight
Body weightGive
2.5–6 kg1 whole tablet once daily
6.1–12 kg2 × 2 whole tablets once daily

Onsior dose by species

SpeciesUseDoseRouteHow oftenBasis
CatsPost-operative pain (tablets)
Cats ≥ 2.5 kg and ≥ 4 months old.
1 mg/kg[1]POOnce daily · Maximum 3 daysLabel
CatsPost-operative pain (injection)
First dose about 30 minutes before surgery.
2 mg/kg[2]SCOnce daily · Maximum 3 daysLabel
DogsPost-operative pain, soft-tissue surgery (injection)
First dose about 45 minutes before surgery.
2 mg/kg[2]SCOnce daily · Maximum 3 daysLabel

Label directions

  • Tablets (cats): 1 mg/kg once a day for up to 3 days — 1 tablet for 2.5–6 kg, 2 tablets for 6.1–12 kg [1].
  • Injection: 2 mg/kg SC once a day for up to 3 days; first dose about 30 minutes (cats) or 45 minutes (dogs) before surgery [2].

Warnings and precautions

  • Do not use the tablets in cats under 2.5 kg (5.5 lb) [1].
  • Robenacoxib can prolong the QT interval [1].
  • Do not give with any other oral or injectable NSAID or corticosteroid [2].
  • Stop if a cat’s appetite drops or it becomes lethargic [2].

About robenacoxib (the active ingredient)

Non-steroidal anti-inflammatory drug (NSAID, coxib — highly COX-2 selective).

How it works

NSAIDs reduce prostaglandin production by inhibiting the cyclooxygenase (COX) enzymes [3]. Robenacoxib is highly selective for COX-2 [3].

Key safety points

  • Do not use the tablets in cats under 2.5 kg (5.5 lb) — they cannot be dosed accurately [1].
  • Robenacoxib has been shown to prolong the QT interval [1].
  • Do not give with any other oral or injectable NSAID or corticosteroid [2].

All about robenacoxib — doses by species and every brand →

Pack sizes

  • Tablets: blister cards of 3 tablets [1].
  • Injection: 20 mL multidose vial; refrigerate and use within 12 weeks of first puncture [2].

Frequently asked questions

What is the Onsior dose for cats?

Tablets 1 mg/kg once a day, or injection 2 mg/kg SC once a day — maximum 3 days either way [1][2].

How many Onsior tablets for a 4 kg cat?

Cats of 2.5–6 kg get 1 whole 6 mg tablet once a day [1].

Can Onsior be used in dogs?

The US injection is labelled for dogs after soft-tissue surgery at 2 mg/kg SC once a day for up to 3 days [2].

Other brands of robenacoxib

More from Elanco

All veterinary products →

Onsior is a trademark of its owner. This page is an independent clinical reference and is not affiliated with Elanco. Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.

Have a case in front of you?Ask WeVet — the AI assistant built for veterinarians. Differentials, treatment plans with calculated doses, drug info from trusted sources and SOAP notes.
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R
Medically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026

References

  1. ONSIOR (robenacoxib) 6 mg tablets for cats — FDA labelingAnimal Drugs @ FDA — US label, Elanco · 2026 · Regulator database
    Passage read from this source
    ONSIOR tablets are available as 6mg round favored tablets in blisters
    The dose of ONSIOR tablets is 0.45mg/lb (1mg/kg) orally once daily, for a maximum of 3 days.
    Do not use in cats weighing less than 5.5 lbs, as cats less than 5.5 lbs cannot be accurately dosed.
    ONSIOR has been shown to prolong the QT interval.
  2. ONSIOR (robenacoxib) injection — FDA labelingAnimal Drugs @ FDA — US label, Elanco · 2026 · Regulator database
    Passage read from this source
    ONSIOR (robenacoxib) injection is available as a 20 mg/mL solution in a 20 mL multidose vial.
    0.91 mg/lb (2 mg/kg) subcutaneously once daily, for a maximum of 3 days
    The first dose should be administered approximately 30 minutes prior to surgery
    The first dose should be administered approximately 45 minutes prior to surgery
  3. Nonsteroidal Anti-inflammatory Drugs in AnimalsMerck Veterinary Manual — S. H. Edwards (updated Sep 2024) · 2024 · Veterinary reference
    Passage read from this source
    Robenacoxib is a coxib-class highly selective COX-2 inhibitor
    Dosage is 2 mg/kg, PO, initially and then 1–2 mg/kg per day thereafter (for up to 6 days in cats).
    NSAIDs act primarily to reduce the biosynthesis of prostaglandins by inhibiting cyclooxygenase (COX).

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

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