Vet product

Deramaxx (Deracoxib) Dose for Dogs: Strengths & Dose Calculator

Reviewed by Dr. Ravi Baraiya, B.V.Sc.Updated 2 Nov 20262 sources

Deramaxx is deracoxib chewable tablets for dogs (12, 25, 75 and 100 mg) made for Elanco ^[1]. Dogs get 1–2 mg/kg once a day for osteoarthritis, or 3–4 mg/kg once a day for up to 7 days after surgery ^[1].

Contains: Deracoxib
Company: Elanco
Forms: Deramaxx 12 mg tablet
Deramaxx 25 mg tablet
Deramaxx 75 mg tablet
Deramaxx 100 mg tablet
Label species: Dogs
Data from: USA (FDA label)
Type: NSAID / pain relief

Deramaxx dose calculator

Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.

Deramaxx strengths and presentations

Presentation	Contains	Strength check
Deramaxx 12 mg tablet PO	Deracoxib 12 mg per chewable^[1]	Confirmed
Deramaxx 25 mg tablet PO	Deracoxib 25 mg per chewable^[1]	Confirmed
Deramaxx 75 mg tablet PO	Deracoxib 75 mg per chewable^[1]	Confirmed
Deramaxx 100 mg tablet PO	Deracoxib 100 mg per chewable^[1]	Confirmed

Deramaxx dose by species

Species	Use	Dose	Route	How often	Basis
Dogs	Osteoarthritis	1–2 mg/kg^[1]	PO	Once daily, as needed	Label
Dogs	Post-operative pain	3–4 mg/kg^[1]	PO	Once daily, as needed · Not more than 7 days	Label

Label directions

Osteoarthritis: 1–2 mg/kg (0.45–0.91 mg/lb) once a day as needed ^[1].
Post-operative pain: 3–4 mg/kg (1.4–1.8 mg/lb) once a day as needed, for no more than 7 days ^[1].

Warnings and precautions

For dogs only — do not use in cats ^[1].
Dogs with known hypersensitivity to deracoxib should not receive Deramaxx ^[1].
Do not dose small dogs by breaking larger tablets ^[1].

About deracoxib (the active ingredient)

Non-steroidal anti-inflammatory drug (NSAID, coxib — COX-2 selective).

How it works

NSAIDs reduce prostaglandin production by inhibiting the cyclooxygenase (COX) enzymes ^[2]. In canine whole-blood assays deracoxib is 12- to 37-fold selective for COX-2 ^[2].

Key safety points

For use in dogs only — do not use in cats ^[1].
Dogs with known hypersensitivity to deracoxib should not receive it ^[1].
Do not try to dose small dogs accurately by breaking larger tablets ^[1].

All about deracoxib — doses by species and every brand →

Pack sizes

12, 25, 75 and 100 mg half-scored tablets in bottles of 7, 30 and 90 ^[1].

Frequently asked questions

What is the Deramaxx dose for dogs?

1–2 mg/kg once a day for osteoarthritis; 3–4 mg/kg once a day for up to 7 days after surgery ^[1].

Can cats take Deramaxx?

No — the label says for use in dogs only, do not use in cats ^[1].

More from Elanco

All veterinary products →

Deramaxx is a trademark of its owner. This page is an independent clinical reference and is not affiliated with Elanco. Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.

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Medically reviewed by

Dr. Ravi Baraiya, B.V.Sc.

Veterinarian · Reviewed 2 Nov 2026

References

DERAMAXX (deracoxib) chewable tablets — FDA labelingAnimal Drugs @ FDA — US label, Elanco · 2026 · Regulator database
Passage read from this source
DERAMAXX tablets are available as 12 mg, 25 mg, 75 mg and 100 mg round, brownish, half-scored tablets in 7, 30, and 90 count bottles.
0.45 – 0.91 mg/lb/day (1 to 2 mg/kg/day) as a single daily dose, as needed.
1.4 – 1.8 mg/lb/day (3 to 4 mg/kg/day) as a single daily dose, as needed, not to exceed 7 days of administration.
For use in dogs only. Do not use in cats.
Nonsteroidal Anti-inflammatory Drugs in AnimalsMerck Veterinary Manual — S. H. Edwards (updated Sep 2024) · 2024 · Veterinary reference
Passage read from this source
Deracoxib, the first NSAID of the coxib class approved for use in dogs
whereas in vitro canine whole blood assays indicate it is 12- to 37-fold selective for COX-2.
NSAIDs act primarily to reduce the biosynthesis of prostaglandins by inhibiting cyclooxygenase (COX).

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.