Galliprant (Grapiprant) Dose for Dogs: Strengths & Dose Calculator
Galliprant is grapiprant tablets for dogs from Elanco, in 20 mg, 60 mg and 100 mg strengths, for osteoarthritis pain and inflammation [1]. The dose is 2 mg/kg once a day [1]. Grapiprant blocks the EP4 prostaglandin receptor rather than the COX enzymes [1].
- Contains
- Grapiprant
- Company
- Elanco
- Forms
- Galliprant 20 mg tablet
Galliprant 60 mg tablet
Galliprant 100 mg tablet - Label species
- Dogs
- Data from
- USA (FDA label)
- Type
- NSAID / pain relief
Galliprant dose calculator
Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.
Galliprant strengths and presentations
Galliprant dose by species
| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Dogs | Osteoarthritis pain and inflammation Label: 0.9 mg/lb (2 mg/kg). | 2 mg/kg[1] | PO | Once daily | Label |
Label directions
Warnings and precautions
About grapiprant (the active ingredient)
Piprant — prostaglandin E2 EP4 receptor antagonist (not a COX inhibitor).
How it works
Grapiprant blocks the EP4 receptor, one of the receptors through which prostaglandin E2 causes pain and inflammation [2][1]. Because it does not inhibit the COX enzymes it works differently from classic NSAIDs [2].
Key safety points
Pack sizes
- 20 mg, 60 mg and 100 mg flavored tablets in bottles of 7, 30 and 90 [1].
Frequently asked questions
What is the Galliprant dose for dogs?
2 mg/kg (0.9 mg/lb) by mouth once a day [1].
Is Galliprant an NSAID?
It is an anti-inflammatory, but it works by blocking the EP4 receptor for prostaglandin E2 rather than inhibiting COX [1].
Can small dogs take Galliprant?
Dogs under 3.6 kg (8 lb) cannot be accurately dosed, and safety below 9 months of age has not been evaluated [1].
Other brands of grapiprant
More from Elanco
Galliprant is a trademark of its owner. This page is an independent clinical reference and is not affiliated with Elanco. Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.
References
- GALLIPRANT (grapiprant tablets) — label
Passage read from this source
20 mg, 60 mg and 100 mg flavored tablets
The dose of GALLIPRANT (grapiprant tablets) is 0.9 mg/lb (2 mg/kg) once daily.
Dogs less than 8 lbs. (3.6 kgs) cannot be accurately dosed.
GALLIPRANT should not be used in dogs that have a hypersensitivity to grapiprant.
- Nonsteroidal Anti-inflammatory Drugs in Animals
Passage read from this source
Grapiprant is a novel PGE2 antagonist, acting at the EP4 receptor.
It is not a COX-1 or COX-2 inhibitor.
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.