Skip to content
WeVet
Active ingredient

Diclofenac for Animals: Mechanism, Doses by Species & Brands

In veterinary medicine diclofenac is used as a 1% topical cream for joint osteoarthritis in horses (Surpass), applied twice a day for up to ten days [1]. India removed diclofenac from veterinary practice in 2006 to protect vultures [2].

Drug class
Non-steroidal anti-inflammatory drug (NSAID)
Brands on this site
Surpass

What diclofenac is used for

  • Horses: pain and inflammation of osteoarthritis in the hock, knee, fetlock and pastern joints — topical cream [1].

How diclofenac works (mechanism of action)

Diclofenac is an NSAID; NSAIDs reduce prostaglandin production by inhibiting cyclooxygenase (COX) [3].

Safety, contraindications and precautions

  • India: diclofenac was removed from veterinary practice in 2006 because it is lethal to vultures [2].
  • Wear gloves when applying the cream [1].
  • Do not use Surpass in horses intended for human consumption [1].

Brands that contain diclofenac

BrandCompanyContainsMarket
SurpassBoehringer Ingelheim Animal HealthDiclofenacUSA (FDA label)

Frequently asked questions

Is veterinary diclofenac allowed in India?

No — it was removed from veterinary practice in India in 2006 to protect vultures [2].

All veterinary products →

Have a case in front of you?Ask WeVet — the AI assistant built for veterinarians. Differentials, treatment plans with calculated doses, drug info from trusted sources and SOAP notes.
Ask WeVet about this
R
Medically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026

References

  1. SURPASS (1% diclofenac sodium) topical cream — FDA labelingAnimal Drugs @ FDA — US label, Boehringer Ingelheim · 2026 · Regulator database
    Passage read from this source
    SURPASS topical cream contains 1% diclofenac sodium.
    Apply a five-inch (5") ribbon of SURPASS topical cream twice daily over the affected joint for up to ten days.
    Wear gloves to prevent absorption into the hands.
    Do not use in horses intended for human consumption.
  2. Bans on two more veterinary drugs linked to vulture deaths in IndiaBirdLife International (news, Sep 2023) · 2023 · Journal article
    Passage read from this source
    to remove Diclofenac from veterinary practice in India in 2006.
  3. Nonsteroidal Anti-inflammatory Drugs in AnimalsMerck Veterinary Manual — S. H. Edwards (updated Sep 2024) · 2024 · Veterinary reference
    Passage read from this source
    NSAIDs act primarily to reduce the biosynthesis of prostaglandins by inhibiting cyclooxygenase (COX).

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

Free AI assistant for vetsSign up free