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Florfenicol for Animals: Mechanism, Doses by Species & Brands

Florfenicol is a phenicol antibiotic used in cattle at 20 mg/kg IM repeated after 48 hours, or 40 mg/kg SC once [1]. Some products combine it with an NSAID for respiratory disease with fever — Resflor Gold with flunixin [2] and Zeleris with meloxicam [3].

Drug class
Antibiotic (phenicol)
Sourced doses for
Cattle
Brands on this site
Resflor Gold, Zeleris

Florfenicol dose calculator

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Florfenicol dose by species

SpeciesUseDoseRouteHow oftenBasis
CattleRespiratory disease (IM)20 mg/kg[1]IMRepeat once after 48 hoursReference
CattleRespiratory disease (SC)40 mg/kg[1]SCOnceReference

What florfenicol is used for

  • Cattle (not veal or lactating dairy cows): bovine respiratory disease [1][2][3].

Safety, contraindications and precautions

  • Not approved in dairy cattle 20 months of age or older [1].

Brands that contain florfenicol

BrandCompanyContainsMarket
Resflor GoldMSD Animal Health (Merck Animal Health in the US)Florfenicol + Flunixin meglumineUSA (FDA label)
ZelerisCeva Animal HealthFlorfenicol + MeloxicamCanada

Frequently asked questions

What is florfenicol combined with?

Resflor Gold combines it with flunixin [2]; Zeleris combines it with meloxicam [3].

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R
Medically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026

References

  1. Dosages of Chloramphenicol and FlorfenicolMerck Veterinary Manual (table) · 2024 · Veterinary reference
    Passage read from this source
    20 mg/kg, IM, repeated in 48 h; 40 mg/kg, SC, once
    Not approved in dairy cattle > 20 months of age
  2. RESFLOR GOLD — labelDrugs.com Vet — US label text, Merck Animal Health · 2026 · Product label
    Passage read from this source
    Each milliliter of sterile RESFLOR GOLD® contains 300 mg florfenicol, 16.5 mg flunixin as flunixin meglumine,
  3. ZELERIS — Canadian labelDrugs.com Vet — Canadian label text, Ceva · 2026 · Product label
    Passage read from this source
    Active ingredients: 400 mg of florfenicol and 5 mg of meloxicam;

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

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