Amoxicillin + clavulanic acid for Animals: Mechanism, Doses by Species & Brands
Amoxicillin–clavulanate combines a bactericidal penicillin with clavulanic acid, a β-lactamase inhibitor [1]. Clavamox chewables are dosed at 6.25 mg/lb (about 13.8 mg/kg) twice daily in dogs and 62.5 mg per cat twice daily [1].
- Drug class
- Penicillin antibiotic with a β-lactamase inhibitor
- Sourced doses for
- Dogs, Cats
- Brands on this site
- Clavamox
Amoxicillin + clavulanic acid dose calculator
Type the strength printed on your own product. Results are calculated in your browser from the cited doses on this page — always check the label of the product you use.
Amoxicillin + clavulanic acid dose by species
| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Dogs | Skin, soft-tissue and periodontal infections Label: 6.25 mg/lb twice a day (= 13.8 mg/kg). Label: 6.25 mg/lb (combined amoxicillin + clavulanate). | 13.8 mg/kg[1] | PO | Twice daily · 5–7 days or 48 h after signs resolve (deep pyoderma up to 21 days); max 30 days | Label |
| Cats | Skin, soft-tissue and urinary infections One 62.5 mg tablet per cat. | 62.5 mg/animal[1] | PO | Twice daily · 5–7 days (UTI 10–14 days or longer); max 30 days | Label |
What amoxicillin + clavulanic acid is used for
How amoxicillin + clavulanic acid works (mechanism of action)
Amoxicillin is bactericidal and inhibits the biosynthesis of cell-wall mucopeptide; clavulanic acid inhibits β-lactamase enzymes and so extends amoxicillin's spectrum [1].
Safety, contraindications and precautions
- Contraindicated in animals with a history of allergy to any penicillin or cephalosporin [1].
Brands that contain amoxicillin + clavulanic acid
Frequently asked questions
What is the amoxicillin–clavulanate dose for dogs?
6.25 mg/lb (about 13.8 mg/kg) of the combined product twice daily [1].
References
- CLAVAMOX (amoxicillin and clavulanate potassium) chewable — label
Passage read from this source
The recommended dosage of CLAVAMOX CHEWABLE Tablet is 6.25 mg/lb of body weight twice a day.
The recommended dosage of CLAVAMOX CHEWABLE Tablet is 62.5 mg twice a day.
Clavulanic acid, an inhibitor of β-lactamase enzymes
contraindicated in animals with a history of allergic reaction to any of the penicillins or cephalosporins
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.