Temaril-P (Trimeprazine + Prednisolone) Dose for Dogs: Strengths & Dose Calculator
Temaril-P tablets for dogs contain trimeprazine 5 mg and prednisolone 2 mg (Zoetis) [1]. They relieve itching of any cause and help in cough; the starting dose goes by weight, twice a day, and is halved after 4 days [1].
- Contains
- Trimeprazine + Prednisolone
- Company
- Zoetis
- Forms
- Temaril-P tablet
- Label species
- Dogs
- Data from
- USA (FDA label)
- Type
- Corticosteroid + antihistamine
Temaril-P dose calculator
Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.
Temaril-P strengths and presentations
| Presentation | Contains | Strength check |
|---|---|---|
| Temaril-P tablet PO | Trimeprazine 5 mg per tablet[1] Prednisolone 2 mg per tablet[1] | Confirmed |
| Body weight | Give |
|---|---|
| 0–10 lb (0–4.5 kg) | ½ tablet twice daily |
| 11–20 lb (5–9.1 kg) | 1 tablet twice daily |
| 21–40 lb (9.5–18.1 kg) | 2 × 2 tablets twice daily |
| Over 40 lb: 3 tablets twice daily | |
Label directions
Warnings and precautions
About trimeprazine (the active ingredient)
Phenothiazine derivative.
Key safety points
- Phenothiazine derivatives may reverse the usual blood-pressure-raising action of epinephrine [1].
About prednisolone (the active ingredient)
Corticosteroid (glucocorticoid, intermediate-acting).
How it works
Glucocorticoids bind receptors in the cell cytoplasm and the hormone–receptor complex changes which proteins the cell makes; one of these, lipocortin, inhibits phospholipase A2, the first step of prostaglandin and leukotriene production [2].
Key safety points
- Contraindicated with uncontrolled infections, diabetes mellitus, hyperadrenocorticism, heart failure, severe kidney insufficiency, corneal or gastro-intestinal ulceration, and in pregnancy [3].
- Do not use with live vaccines [3].
- Give in the morning to dogs and in the evening to cats, to match their natural cortisol peak [3].
- Long-term use may cause iatrogenic Cushing’s syndrome; stopping suddenly may lead to an Addisonian-like crisis; alternate-day dosing reduces adrenal suppression [2].
- Glucocorticoids may trigger or worsen diabetes mellitus [2].
Pack sizes
- Bottles of 100 and 1000 tablets [1].
Frequently asked questions
What is in Temaril-P?
Trimeprazine 5 mg and prednisolone 2 mg per tablet [1].
How much Temaril-P for a 15 lb dog?
1 tablet twice a day to start (11–20 lb), halved after 4 days [1].
Other brands of trimeprazine + prednisolone
More from Zoetis
Temaril-P is a trademark of its owner. This page is an independent clinical reference and is not affiliated with Zoetis. Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.
References
- TEMARIL-P tablets — label
Passage read from this source
equivalent to trimeprazine, 5 mg, and prednisolone, 2 mg.
Antipruritic: Temaril-P is recommended for the relief of itching regardless of cause.
Antitussive: Temaril-P has been found to be effective therapy and adjunctive therapy in various cough conditions of dogs.
After 4 days, reduce dosage to 1/2 of the initial dose or to an amount just sufficient to maintain remission of symptoms.
- Corticosteroids in Animals
Passage read from this source
Glucocorticoid-specific receptors in the cell cytoplasm bind with steroid ligands to form hormone-receptor complexes
Such proteins include lipocortin, a protein known to inhibit PLA2alpha
anti-inflammatory dosages (prednisolone, 0.5–1 mg/kg per day) alleviate pruritus
Longterm administration may lead to iatrogenic Cushing syndrome
- Prednicare 5 mg tablets — SPC
Passage read from this source
DOGS: 0.1-2.0 mg/kg/day
CATS: 0.1-2.0 mg/kg/day
The lowest effective dose must be used.
treatment may be given for one to three weeks at doses between:
- Prednidale 25 mg tablets for dogs — SPC
Passage read from this source
Dose: 0.1 - 2.0 mg per kg bodyweight per day.
administration for one to three weeks at the above dosage levels may be required.
For the treatment of inflammatory and allergic diseases, including some autoimmune diseases
Do not use in animals with renal insufficiency, diabetes mellitus or corneal ulceration.
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.