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Resflor Gold (Florfenicol + Flunixin meglumine) Dose for Cattle: Strengths & Dose Calculator

Resflor Gold combines florfenicol 300 mg/mL with flunixin 16.5 mg/mL (Merck Animal Health) for bovine respiratory disease and its fever in beef and non-lactating dairy cattle [1]. It is a single SC dose of 6 mL per 100 lb — 40 mg/kg florfenicol and 2.2 mg/kg flunixin [1].

Contains
Florfenicol + Flunixin meglumine
Company
MSD Animal Health (Merck Animal Health in the US)
Forms
Resflor Gold injection
Label species
Cattle
Data from
USA (FDA label)
Type
NSAID + antibiotic

Resflor Gold dose calculator

mg per mL
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Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.

Resflor Gold strengths and presentations

PresentationContainsStrength check
Resflor Gold injection
SC
Florfenicol 300 mg per mL[1]
Flunixin meglumine 16.5 mg per mL[1]
Confirmed

Resflor Gold dose by species

SpeciesUseDoseRouteHow oftenBasis
CattleBovine respiratory disease with fever
Gives 2.2 mg/kg flunixin at the same time. Not more than 10 mL per injection site.
40 mg/kg[1]SCOnceLabel

Label directions

  • Give once SC: 40 mg/kg florfenicol + 2.2 mg/kg flunixin (6 mL per 100 lb) [1].
  • No more than 10 mL at each site [1].

Warnings and precautions

  • Not approved for female dairy cattle 20 months of age or older, including dry cows [1].
  • Do not use in calves to be processed for veal or in animals intended for breeding [1].

Withdrawal periods

SpeciesProductWithdrawalDetail
CattleMeat38 daysNot slaughtered within 38 days of treatment.[1]

About florfenicol (the active ingredient)

Antibiotic (phenicol).

Key safety points

  • Not approved in dairy cattle 20 months of age or older [2].

All about florfenicol — doses by species and every brand →

About flunixin meglumine (the active ingredient)

Non-steroidal anti-inflammatory drug (NSAID, nicotinic acid derivative — non-selective).

How it works

NSAIDs reduce prostaglandin production by inhibiting the cyclooxygenase (COX) enzymes [4]. Flunixin is a non-selective COX inhibitor [4].

Key safety points

  • Banamine injection is approved only for IV use in cattle — IM injection has left violative residues in meat [5].
  • Not for use in dry dairy cows, veal calves, breeding bulls or horses intended for food (Banamine label) [5].
  • Pour-on: do not use in animals with liver, kidney or heart disease, gut ulceration or platelet disorders [6].

All about flunixin meglumine — doses by species and every brand →

Pack sizes

  • 100, 250 and 500 mL multi-dose vials [1].

Frequently asked questions

What is the Resflor Gold dose?

One SC injection of 6 mL per 100 lb — 40 mg/kg florfenicol and 2.2 mg/kg flunixin [1].

What is the meat withdrawal for Resflor Gold?

38 days [1].

Other brands of florfenicol + flunixin meglumine

More from MSD Animal Health (Merck Animal Health in the US)

All veterinary products →

Resflor Gold is a trademark of its owner. This page is an independent clinical reference and is not affiliated with MSD Animal Health (Merck Animal Health in the US). Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.

Have a case in front of you?Ask WeVet — the AI assistant built for veterinarians. Differentials, treatment plans with calculated doses, drug info from trusted sources and SOAP notes.
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R
Medically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026

References

  1. RESFLOR GOLD — labelDrugs.com Vet — US label text, Merck Animal Health · 2026 · Product label
    Passage read from this source
    Each milliliter of sterile RESFLOR GOLD® contains 300 mg florfenicol, 16.5 mg flunixin as flunixin meglumine,
    40 mg florfenicol/kg body weight and 2.2 mg flunixin/kg body weight (6 mL/100 lb)
    should be administered once by subcutaneous injection
    Do not administer more than 10 mL at each site.
  2. Dosages of Chloramphenicol and FlorfenicolMerck Veterinary Manual (table) · 2024 · Veterinary reference
    Passage read from this source
    20 mg/kg, IM, repeated in 48 h; 40 mg/kg, SC, once
    Not approved in dairy cattle > 20 months of age
  3. ZELERIS — Canadian labelDrugs.com Vet — Canadian label text, Ceva · 2026 · Product label
    Passage read from this source
    Active ingredients: 400 mg of florfenicol and 5 mg of meloxicam;
  4. Nonsteroidal Anti-inflammatory Drugs in AnimalsMerck Veterinary Manual — S. H. Edwards (updated Sep 2024) · 2024 · Veterinary reference
    Passage read from this source
    In the US, the nicotinic acid derivative flunixin (as the meglumine salt) is approved for use in horses
    Flunixin is a nonselective COX inhibitor.
    A topical formulation also has been approved for use in cattle.
    NSAIDs act primarily to reduce the biosynthesis of prostaglandins by inhibiting cyclooxygenase (COX).
  5. BANAMINE (flunixin meglumine injection) — labelDrugs.com Vet — US label text, Merck Animal Health · 2026 · Product label
    Passage read from this source
    The recommended dose for musculoskeletal disorders is 0.5 mg per pound (1 mL/100 lbs) of body weight once daily.
    Treatment may be given by intravenous or intramuscular injection and repeated for up to 5 days.
    1.1 to 2.2 mg/kg (0.5 to 1 mg/lb; 1 to 2 mL per 100 lbs) of body weight given by slow intravenous administration
    either once a day as a single dose or divided into two doses administered at 12-hour intervals for up to 3 days.
  6. BANAMINE Transdermal (flunixin pour-on) — Canadian labelDrugs.com Vet — Canadian label text, Merck Animal Health · 2026 · Product label
    Passage read from this source
    Apply a single total dose of 3.3 mg flunixin per kg bodyweight (equivalent to 1 mL/15 kg bodyweight) topically
    Treated cattle must not be slaughtered for use in food for at least 13 days after the latest treatment with this drug.
    Do not use in animals with hepatic disease, renal and cardiovascular impairment,
  7. MEGLUDYNE Injection — product pageVirbac India — official product page · 2026 · Official company page
    Passage read from this source
    1.1 mg to 2.2 mg FLUNIXIN per kg body weight or 1 ml to 2 ml of MEGLUDYNE per 45 kg body weight,
    1 mg FLUNIXIN per kg body weight given by slow I/V or I/M injection route.
    1 mg to 2 mg FLUNIXIN per kg body weight given by S/C or slow I/V.

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

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