Equipalazone (Phenylbutazone) Dose for Horses: Strengths & Dose Calculator
Equipalazone is phenylbutazone (“bute”) oral powder — 1 g per sachet — for horses and ponies from Dechra [1]. A 450 kg horse gets two sachets twice on day 1 (8.8 mg/kg/day), one sachet twice a day for four days, then one sachet daily or on alternate days [1].
- Contains
- Phenylbutazone
- Company
- Dechra
- Forms
- Equipalazone 1 g sachet
- Label species
- Horses
- Data from
- United Kingdom
- Type
- NSAID / pain relief
Equipalazone dose calculator
Results are calculated in your browser from the doses and strengths on this page. Check the strength printed on your pack and the label in your country before giving any dose.
Equipalazone strengths and presentations
| Presentation | Contains | Strength check |
|---|---|---|
| Equipalazone 1 g sachet PO (in feed) | Phenylbutazone 1 g per sachet[1] | Confirmed |
Equipalazone dose by species
Label directions
Warnings and precautions
- Not for horses intended for human consumption — treated horses may never be slaughtered for food [1].
- Low therapeutic index — do not exceed the dose or duration [1].
- Do not give with another NSAID or within 24 hours of one [1].
- Do not use with heart, liver or kidney disease, risk of gut ulceration or bleeding, or blood dyscrasia [1].
About phenylbutazone (the active ingredient)
Non-steroidal anti-inflammatory drug (NSAID, pyrazolone).
How it works
NSAIDs reduce prostaglandin production by inhibiting the cyclooxygenase (COX) enzymes [2].
Key safety points
- Its therapeutic index is low — do not exceed the dose or the duration [1].
- Do not use in animals with heart, liver or kidney disease, gut ulceration or bleeding, or blood dyscrasia, or within 24 hours of another NSAID [1].
- Treated horses may never be slaughtered for human consumption [1].
All about phenylbutazone — doses by species and every brand →
Pack sizes
- 32 or 100 sachets [1].
Frequently asked questions
How many Equipalazone sachets for a 500 kg horse?
The SPC is written for a 450 kg horse: 2 sachets twice on day 1, 1 sachet twice daily for 4 days, then 1 sachet daily or every other day [1].
Can a horse on bute go for meat?
No — treated horses may never be slaughtered for human consumption [1].
More from Dechra
Equipalazone is a trademark of its owner. This page is an independent clinical reference and is not affiliated with Dechra. Strengths, species and withdrawal periods can differ between countries — always follow the pack insert in your country.
References
- Equipalazone 1 g oral powder for horses and ponies — SPC
Passage read from this source
Phenylbutazone 1 g
Horses 450 kg (1000 lb) body weight: the contents of two sachets to be administered twice on day 1 of treatment
(equivalent to 8.8 mg/kg/day) followed by the contents of one sachet twice daily for four days (4.4 mg/kg/day)
then one sachet daily, or on alternate days, sufficient to keep the horse comfortable (2.2 mg/kg/day).
- Nonsteroidal Anti-inflammatory Drugs in Animals
Passage read from this source
phenylbutazone (PBZ) is a pyrazolone derivative available in tablet, paste, gel, and parenteral formulations
PBZ dosages of 3–7 mg/kg, PO, every 8 hours, are recommended in dogs.
NSAIDs act primarily to reduce the biosynthesis of prostaglandins by inhibiting cyclooxygenase (COX).
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.