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Anion Gap Calculator for Dogs & Cats

Anion gap from sodium, potassium, chloride and bicarbonate.

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How it is calculated

Anion gap = (Na⁺ + K⁺) − (Cl⁻ + HCO₃⁻) [1].

An increased anion gap is usually due to increased unmeasured anions and reflects metabolic acidosis — for example lactate, ketoacids, renal acids or exogenous agents such as ethylene glycol [1]. Compare with your laboratory's reference interval.

Worked example

(145 + 4) − (110 + 20) = 19 mEq/L.

Frequently asked questions

What does an increased anion gap mean?

An increased anion gap is usually due to increased unmeasured anions and reflects metabolic acidosis, for example lactate, ketoacids, renal acids or ethylene glycol [1].

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References

  1. Anion gap — Veterinary Clinical Pathology: An IntroductionM. Jackson, B. Kidney, N. Fernandez — University of Saskatchewan (open textbook)

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

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