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Triamcinolone acetonide for Animals: Mechanism, Doses by Species & Brands

Triamcinolone acetonide is a glucocorticoid. The US regulation for the injectable suspension allows 0.05–0.1 mg/lb IM or SC in dogs and cats and 0.01–0.02 mg/lb in horses [2]; Genesis is a 0.015% topical spray for allergic itch in dogs [1].

Drug class
Corticosteroid (glucocorticoid)
Sourced doses for
Dogs, Cats, Horses
Brands on this site
Genesis Topical Spray

Triamcinolone acetonide dose calculator

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Triamcinolone acetonide dose by species

SpeciesUseDoseRouteHow oftenBasis
DogsInflammatory, arthritic or allergic disorders (injection)
Regulation: 0.05–0.1 mg/lb — works out to 0.11–0.22 mg/kg (calculated).
0.11–0.22 mg/kg[2]IM or SCLabel
CatsInflammatory, arthritic or allergic disorders (injection)
Regulation: 0.05–0.1 mg/lb — works out to 0.11–0.22 mg/kg (calculated).
0.11–0.22 mg/kg[2]IM or SCLabel
HorsesInflammation (injection)
Regulation: 0.01–0.02 mg/lb — works out to 0.022–0.044 mg/kg (calculated); usual dose 12–20 mg.
0.022–0.044 mg/kg[2]IM or SCSingle injectionLabel

What triamcinolone acetonide is used for

  • Dogs and cats: inflammation, acute arthritis, allergic and skin disorders — injection [2].
  • Horses: inflammation — injection [2].
  • Dogs: itch of allergic dermatitis — topical spray (Genesis) [1].

How triamcinolone acetonide works (mechanism of action)

Glucocorticoids bind receptors in the cell cytoplasm and the hormone–receptor complex changes which proteins the cell makes; one of these, lipocortin, inhibits phospholipase A2, the first step of prostaglandin and leukotriene production [3].

Safety, contraindications and precautions

  • Injectable triamcinolone must not be used in horses intended for human consumption [2].
  • Wear gloves when applying the spray and keep it out of the dog’s eyes [1].

Brands that contain triamcinolone acetonide

BrandCompanyContainsMarket
Genesis Topical SprayVirbacTriamcinolone acetonideUSA (FDA label)

Frequently asked questions

What is the triamcinolone injection dose for dogs?

The US regulation allows 0.05–0.1 mg per lb (about 0.11–0.22 mg/kg, calculated) IM or SC [2].

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R
Medically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026

References

  1. GENESIS (triamcinolone acetonide) topical spray — package insertVirbac US — official package insert · 2026 · Official company page
    Passage read from this source
    Each mL of GENESIS Topical Spray contains 0.15 mg triamcinolone acetonide
    GENESIS Topical Spray is indicated for the control of pruritus associated with allergic dermatitis in dogs.
    Wear gloves when applying the product.
    Avoid getting the spray in dog's eyes.
  2. 21 CFR § 522.2483 — Triamcinolone acetonide suspensionUS Code of Federal Regulations (via Cornell LII) · 2026 · Regulator database
    Passage read from this source
    Each milliliter of suspension contains 2 or 6 milligrams (mg) triamcinolone acetonide.
    For inflammatory, arthritic, or allergic disorders, administer 0.05 to 0.1 mg per pound (/lb) of body weight
    Administer 0.01 to 0.02 mg/lb of body weight as a single injection.
    Usual dose is 12 to 20 mg.
  3. Corticosteroids in AnimalsMerck Veterinary Manual · 2024 · Veterinary reference
    Passage read from this source
    Glucocorticoid-specific receptors in the cell cytoplasm bind with steroid ligands to form hormone-receptor complexes
    Such proteins include lipocortin, a protein known to inhibit PLA2alpha

For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.

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