# Tolfedine (Tolfenamic acid) Dose for Dogs & Cats: Strengths & Dose Calculator

> Tolfedine is tolfenamic acid from Vetoquinol; the 4% injection holds 40 mg/mL. Dogs with hip-dysplasia osteoarthritis get 4 mg/kg by injection then tablets for 2–4 more days; cats with fever get 4…

- Source page: https://wevet.in/vet-products/tolfedine-tolfenamic-acid/
- Type: Vet product
- Publisher: WeVet
- Updated: 2026-11-02
- Medically reviewed by: Dr. Ravi Baraiya, B.V.Sc. (2026-11-02)
- Audience: veterinarians and veterinary students

Tolfedine is tolfenamic acid from Vetoquinol; the 4% injection holds 40 mg/mL [1]. Dogs with hip-dysplasia osteoarthritis get 4 mg/kg by injection then tablets for 2–4 more days; cats with fever get 4 mg/kg a day by mouth for 3–5 days [1].

- Brand: Tolfedine
- Contains: Tolfenamic acid
- Company: Vetoquinol
- Label species: Dogs, Cats
- Data from: Canada

## Strengths

- Tolfedine 4% injection (40 mg/mL): Tolfenamic acid 40 mg per mL (verified, [1])

## Dose by species

| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Dogs | Osteoarthritis (hip dysplasia) | 4 mg/kg [1] | SC or IM, then tablets | Once daily · Injection, then tablets 2–4 more days; may be repeated weekly | Label |
| Cats | Fever | 4 mg/kg [1] | PO | Once daily · 3–5 days | Label |

## Label directions

- Dogs: 4 mg/kg SC or IM, then Tolfedine tablets at the same dose for 2–4 more days; may be repeated once a week [1].
- Cats: 4 mg/kg by mouth once a day for 3–5 days [1].

## Warnings and precautions

- Contraindicated with gastro-duodenal ulcers or severe kidney, heart or liver disorders [1].
- Contraindicated in dehydrated, hypovolaemic or hypotensive animals [1].
- Not advised in breeding, pregnant or lactating animals [1].


Interactive dose calculator (strength prefilled only when confirmed): use the page link above.

## Frequently asked questions

### What is the Tolfedine dose for dogs?

4 mg/kg of tolfenamic acid by injection, then tablets at the same dose for 2–4 more days [1].

## References

[1] TOLFEDINE 4% Injection — Canadian label — Drugs.com Vet — Canadian label text, Vetoquinol (2026). https://drugs.com/vet/tolfedine-4-injection-can.html
[2] Nonsteroidal Anti-inflammatory Drugs in Animals — Merck Veterinary Manual — S. H. Edwards (updated Sep 2024) (2024). https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals

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Numbers in [brackets] cite the references above. For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.
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