# Equipalazone (Phenylbutazone) Dose for Horses: Strengths & Dose Calculator

> Equipalazone is phenylbutazone (“bute”) oral powder — 1 g per sachet — for horses and ponies from Dechra. A 450 kg horse gets two sachets twice on day 1 (8.8 mg/kg/day), one…

- Source page: https://wevet.in/vet-products/equipalazone-phenylbutazone/
- Type: Vet product
- Publisher: WeVet
- Updated: 2026-11-02
- Medically reviewed by: Dr. Ravi Baraiya, B.V.Sc. (2026-11-02)
- Audience: veterinarians and veterinary students

Equipalazone is phenylbutazone (“bute”) oral powder — 1 g per sachet — for horses and ponies from Dechra [1]. A 450 kg horse gets two sachets twice on day 1 (8.8 mg/kg/day), one sachet twice a day for four days, then one sachet daily or on alternate days [1].

- Brand: Equipalazone
- Contains: Phenylbutazone
- Company: Dechra
- Label species: Horses
- Data from: United Kingdom

## Strengths

- Equipalazone 1 g sachet: Phenylbutazone 1 g per sachet (verified, [1])

## Dose by species

| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Horses | Day 1 | 8.8 mg/kg [1] | PO | Split in two doses | Label |
| Horses | Days 2–5 | 4.4 mg/kg [1] | PO | Split in two doses · 4 days | Label |
| Horses | Maintenance (Ponies (225 kg): one sachet on alternate days.) | 2.2 mg/kg [1] | PO | Once daily or on alternate days | Label |

## Label directions

- Horse 450 kg: 2 sachets twice on day 1; 1 sachet twice daily for 4 days; then 1 sachet daily or on alternate days [1].
- Pony 225 kg: 1 sachet (4.4 mg/kg) on alternate days [1].
- Stop if there is no response after 4–5 days [1].

## Warnings and precautions

- Not for horses intended for human consumption — treated horses may never be slaughtered for food [1].
- Low therapeutic index — do not exceed the dose or duration [1].
- Do not give with another NSAID or within 24 hours of one [1].
- Do not use with heart, liver or kidney disease, risk of gut ulceration or bleeding, or blood dyscrasia [1].


Interactive dose calculator (strength prefilled only when confirmed): use the page link above.

## Frequently asked questions

### How many Equipalazone sachets for a 500 kg horse?

The SPC is written for a 450 kg horse: 2 sachets twice on day 1, 1 sachet twice daily for 4 days, then 1 sachet daily or every other day [1].

### Can a horse on bute go for meat?

No — treated horses may never be slaughtered for human consumption [1].

## References

[1] Equipalazone 1 g oral powder for horses and ponies — SPC — UK Veterinary Medicines Directorate — Dechra SPC (2026). https://www.vmd.defra.gov.uk/ProductInformationDatabase/files/SPC_Documents/SPC_1200428.PDF
[2] Nonsteroidal Anti-inflammatory Drugs in Animals — Merck Veterinary Manual — S. H. Edwards (updated Sep 2024) (2024). https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals

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Numbers in [brackets] cite the references above. For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.
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