Ibuprofen Toxicity Calculator for Dogs & Cats
Ibuprofen dose in mg/kg after an acute ingestion and the expected effects at that dose.
Results are calculated in your browser. Always double-check before administering and use your clinical judgement.
How it is calculated
Dose (mg/kg) = total mg ÷ body weight (kg).
Dogs, single acute ingestion: 100–125 mg/kg GI signs; 175–300 mg/kg renal failure; > 400 mg/kg CNS effects plus renal and GI signs; > 600 mg/kg potentially lethal. Cats are susceptible at approximately half the dose that causes toxicosis in dogs [1].
Worked example
2000 mg in a 10 kg dog = 200 mg/kg (renal failure range).
Frequently asked questions
What dose of ibuprofen is toxic to dogs?
After a single acute ingestion, 100–125 mg/kg can cause GI signs, 175–300 mg/kg renal failure, more than 400 mg/kg CNS effects, and more than 600 mg/kg is potentially lethal [1].
Are cats more sensitive to ibuprofen?
Yes — cats are susceptible at approximately half the dose required to cause toxicosis in dogs [1].
More toxicology calculators
References
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.