# Trimeprazine for Animals: Mechanism, Doses by Species & Brands

> Trimeprazine is a phenothiazine derivative. In Temaril-P tablets for dogs it is combined with prednisolone (5 mg trimeprazine + 2 mg prednisolone) to relieve itching and as cough therapy.

- Source page: https://wevet.in/active-ingredients/trimeprazine/
- Type: Active ingredient
- Publisher: WeVet
- Updated: 2026-11-02
- Medically reviewed by: Dr. Ravi Baraiya, B.V.Sc. (2026-11-02)
- Audience: veterinarians and veterinary students

Trimeprazine is a phenothiazine derivative [1]. In Temaril-P tablets for dogs it is combined with prednisolone (5 mg trimeprazine + 2 mg prednisolone) to relieve itching and as cough therapy [1].

- Class: Phenothiazine derivative
- Brands: Temaril-P

## Dose by species

## Uses

- Dogs: relief of itching and adjunct therapy of cough (Temaril-P) [1].

## Safety

- Phenothiazine derivatives may reverse the usual blood-pressure-raising action of epinephrine [1].


## Frequently asked questions

### What is trimeprazine combined with?

In Temaril-P it is combined with prednisolone — 5 mg trimeprazine and 2 mg prednisolone per tablet [1].

## References

[1] TEMARIL-P tablets — label — Drugs.com Vet — US label text, Zoetis (2026). https://drugs.com/vet/temaril-p-tablets.html

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Numbers in [brackets] cite the references above. For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.
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