Active ingredient
Fluralaner for Animals: Mechanism, Doses by Species & Brands
Fluralaner is an isoxazoline flea and tick drug; Bravecto chews are given to dogs at a minimum of 25 mg/kg once every 12 weeks [1].
- Drug class
- Isoxazoline ectoparasiticide
- Sourced doses for
- Dogs
- Brands on this site
- Bravecto
Fluralaner dose calculator
Type the strength printed on your own product. Results are calculated in your browser from the cited doses on this page — always check the label of the product you use.
Fluralaner dose by species
| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Dogs | Fleas and ticks Minimum dose; given as whole chews by weight band. | 25 mg/kg[1] | PO | Every 12 weeks (every 8 weeks for lone star tick) | Label |
What fluralaner is used for
- Dogs from 6 months and 4.4 lb: fleas and ticks for 12 weeks; lone star tick for 8 weeks [1].
How fluralaner works (mechanism of action)
Fluralaner inhibits the arthropod nervous system by antagonising ligand-gated chloride channels [1].
Safety, contraindications and precautions
- Isoxazolines have been associated with neurologic adverse reactions including tremors, ataxia and seizures — use with caution in dogs with a history of seizures [1].
Brands that contain fluralaner
| Brand | Company | Contains | Market |
|---|---|---|---|
| Bravecto | MSD Animal Health (Merck Animal Health in the US) | Fluralaner | USA (FDA label) |
Frequently asked questions
How often is fluralaner given?
Once every 12 weeks for fleas and most ticks, or every 8 weeks where lone star ticks are a risk [1].
Have a case in front of you?Ask WeVet — the AI assistant built for veterinarians. Differentials, treatment plans with calculated doses, drug info from trusted sources and SOAP notes.
Ask WeVet about thisMedically reviewed by
Dr. Ravi Baraiya, B.V.Sc.
Veterinarian · Reviewed 2 Nov 2026
References
- BRAVECTO (fluralaner) chewable — label
Passage read from this source
minimum dose of 11.4 mg/lb (25 mg/kg) body weight
administered orally as a single dose every 12 weeks
The mode of action of fluralaner is the antagonism of the ligand-gated chloride channels
Use with caution in dogs with a history of seizures or neurologic disorders.
For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.