# Clorsulon for Animals: Mechanism, Doses by Species & Brands

> Clorsulon is a flukicide combined with ivermectin in injections such as Hitek F (100 mg/mL clorsulon with 10 mg/mL ivermectin). At 1 mL per 50 kg this works out to 2 mg/kg…

- Source page: https://wevet.in/active-ingredients/clorsulon/
- Type: Active ingredient
- Publisher: WeVet
- Updated: 2026-11-02
- Medically reviewed by: Dr. Ravi Baraiya, B.V.Sc. (2026-11-02)
- Audience: veterinarians and veterinary students

Clorsulon is a flukicide combined with ivermectin in injections such as Hitek F (100 mg/mL clorsulon with 10 mg/mL ivermectin) [2]. At 1 mL per 50 kg this works out to 2 mg/kg of clorsulon (calculated from [2]).

- Class: Flukicide (benzenesulfonamide)
- Brands: Hitek F

## Dose by species

| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Cattle | Liver flukes (with ivermectin, as Hitek F) (Calculated from the label: 1 mL per 50 kg of 100 mg/mL clorsulon. Calculated: 100 mg/mL × 1 mL per 50 kg = 2 mg/kg.) | 2 mg/kg [2] | SC | Single dose | Label |

## Uses

- Bovines, sheep, goats and camels: fascioliasis (liver flukes), together with ivermectin for worms and external parasites (Hitek F) [2].

## Mechanism of action

Clorsulon is a competitive inhibitor of glycolysis [1].


## Frequently asked questions

### How does clorsulon work?

Clorsulon is a competitive inhibitor of glycolysis in the fluke [1].

## References

[1] Pharmacodynamics: Mechanisms of Anthelmintic Action in Animals — Merck Veterinary Manual — E. Claerebout & C. E. Lanusse (Apr 2025) (2025). https://www.merckvetmanual.com/pharmacology/anthelmintics/pharmacodynamics-mechanisms-of-anthelmintic-action-in-animals
[2] HITEK™ F Injection — Virbac India (official product page) (2026). https://in.virbac.com/products/ectoparasiticide/hitek-f-injection

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Numbers in [brackets] cite the references above. For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.
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