# Cimicoxib for Animals: Mechanism, Doses by Species & Brands

> Cimicoxib is a coxib-class NSAID used in dogs at 2 mg/kg by mouth once a day for osteoarthritis and for pain around surgery (Cimalgex).

- Source page: https://wevet.in/active-ingredients/cimicoxib/
- Type: Active ingredient
- Publisher: WeVet
- Updated: 2026-11-02
- Medically reviewed by: Dr. Ravi Baraiya, B.V.Sc. (2026-11-02)
- Audience: veterinarians and veterinary students

Cimicoxib is a coxib-class NSAID [2] used in dogs at 2 mg/kg by mouth once a day for osteoarthritis and for pain around surgery (Cimalgex) [1].

- Class: Non-steroidal anti-inflammatory drug (NSAID, coxib)
- Brands: Cimalgex

## Dose by species

| Species | Use | Dose | Route | How often | Basis |
|---|---|---|---|---|---|
| Dogs | Osteoarthritis | 2 mg/kg [1] | PO | Once daily · Up to 6 months, with regular monitoring for longer use | Label |
| Dogs | Peri-operative pain | 2 mg/kg [1] | PO | Once daily · One dose 2 hours before surgery, then 3–7 days | Label |

## Uses

- Dogs: pain and inflammation of osteoarthritis, and peri-operative pain from orthopaedic or soft-tissue surgery [1].

## Mechanism of action

NSAIDs reduce prostaglandin production by inhibiting the cyclooxygenase (COX) enzymes [2]. Cimicoxib belongs to the coxib (COX-2 selective) group [2].

## Safety

- Do not use in dogs under 10 weeks of age; monitor dogs under 6 months closely [1].
- Do not use in dogs with gastrointestinal or haemorrhagic disorders, or in breeding, pregnant or lactating animals [1].
- Do not use together with corticosteroids or other NSAIDs [1].


## Frequently asked questions

### What is the cimicoxib dose for dogs?

2 mg/kg by mouth once a day; for surgery, one dose 2 hours before and then 3–7 days [1].

## References

[1] Cimalgex chewable tablets for dogs — SPC — UK Veterinary Medicines Directorate — Vetoquinol SPC (2026). https://www.vmd.defra.gov.uk/ProductInformationdatabase/files/SPC_Documents/SPC_2740970.PDF
[2] Nonsteroidal Anti-inflammatory Drugs in Animals — Merck Veterinary Manual — S. H. Edwards (updated Sep 2024) (2024). https://www.merckvetmanual.com/pharmacology/inflammation/nonsteroidal-anti-inflammatory-drugs-in-animals

---
Numbers in [brackets] cite the references above. For veterinary professionals. Information supports — never replaces — clinical judgement; always check the current product label and local regulations.
Ask follow-up questions in WeVet (free AI assistant for veterinarians): https://wevet.in/